When you scratch an itch, it actually disappears.
Give everyone the ability to change their skin color at will.
It’s a threeway tie for me:
Option 1) Everyone now has a minimim IQ of 140.
Option 2) Everyones empathy part of the brain increases dramatically.
Option 3) Addiction becomes impossible
I would adjust dopamine responses so things that are good for people, etc. Exercise, learning, and generaly improving themselves, hold a stronger attraction and pleasurable experience than those that cause harm, drinking, smoking, and drug use.
Nails stop growing just after they get even with the end of the fingertip.
… I hate clipping my finger nails.